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. 2017 Jan 19;15:6. doi: 10.1186/s12964-016-0159-5

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© The Author(s) 2017

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Interaction graph and overview of hypothesis for mTORC2 regulation. Black lines indicate edges that are mandatory and green lines have edge labels allowing for uncertainty annotated with their respective edge label. a List of logical functions for components with known regulation, where the notation signifies a logical AND as ∧, OR as ∨ and negation as ¬. b List of candidate regulators for mTORC2 in the literature