Table 5.

Effect of siRNA treatment on microfilaria release by female B. malayi adult parasites

Time (h)	% inhibition in microfilaria release (mean ± SD)
	SCR	siRNA1	siRNA2	siRNA1 + 2
24	4.60 ± 0.85	75.4 ± 2.26***	73.9 ± 5.59***	79.4 ± 2.20***
48	5.3 ± 1.25	79.7 ± 1.84***	80.0 ± 2.97***	81.2 ± 1.96***
72	4.3 ± 0.71	85.3 ± 1.69***	84.7 ± 2.97***	86.3 ± 1.20***
96	3.7 ± 1.56	88.3 ± 0.99***	87.9 ± 2.26***	88.8 ± 1.69***
120	3.6 ± 1.56	89.5 ± 0.71***	89.2 ± 2.26***	90.3 ± 0.99***

Abbreviations: MC medium control; SCR negative control (scrambled siRNA); SD standard deviation

***P < 0.001