Table 2. Selection criteria of LT for patients with HCC.
| Authors | Criteria or institute | Year | Variables |
|---|---|---|---|
| Criteria based on morphology of HCC | |||
| Mazzaferro (6) | Milan | 1996 | (I) Number ≤3, size ≤3 cm; (II) single tumor, size ≤5 cm |
| Yao (20) | UCSF | 2001 | (I) Single tumor, size ≤6.5 cm; (II) number ≤3, size <4.5 cm, total tumor diameter ≤8 cm |
| Mazzaferro (32) | Up to seven | 2009 | Largest tumor size + number <7 |
| Li (34) | Chengdu | 2009 | Total tumor diameter ≤9 cm |
| Criteria incorporating serum tumor marker | |||
| Takada (41) | Kyoto | 2007 | Number ≤10, size ≤5 cm, DCP ≤400 mAU/mL |
| Soejima (43) | Kyusyu | 2007 | Size ≤5 cm, DCP ≤300 mAU/mL |
| Zheng (33) | Hangzhou | 2008 | (I) Total tumor diameter ≤8 cm; (II) total tumor diameter >8 cm, well or moderate differentiated, AFP <400 ng/mL |
| Toso (47) | Alberta | 2009 | Total tumor volume ≤115 cm3, AFP ≤400 ng/mL |
| Duvoux (48) | Liver Transplantation French Study Group | 2012 | (I) Number ≤3, size ≤6 cm, AFP ≤100 ng/mL; (II) number ≥4, size ≤3 cm, AFP ≤100 ng/mL |
| Shindoh (49) | Tokyo | 2014 | (I) Number ≤5, size ≤5 cm, and AFP ≤250 ng/mL or DCP ≤450 mAU/mL; (II) AFP ≤250 ng/mL and DCP ≤450 mAU/mL |
LT, liver transplantation; HCC, hepatocellular carcinoma; DCP, des-gamma-carboxyprothrombin; AFP, alpha-fetoprotein.