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The most potent neutralizing antibodies bind with high affinity to preF and recognize antigenic sites Ø and V. (A) Neutralization IC50 is plotted against apparent preF KD and colored according to antigenic site. N.N., non-neutralizing; N.B., non-binder. (B) Neutralization IC50 is plotted against apparent postF KD and colored by antigenic site. (C) Antibodies are grouped according to neutralization potency and colored by antigenic site.
