Figure 6.

Diet STZ-induced diabetic rats were treated with 100 mg/kg met (DH) and AAP (100 and 400 mg/kg) for four weeks. The levels of (A) IFN-γ, (B) TNF-α, (C) IL-2 and (D) NF-κB in serum were determined. Data are expressed as the mean + standard error (n=10) and analyzed using a one-way analysis of variance followed by Dunn's test. ^#P<0.05, ^##P<0.01 vs. CT; *P<0.05, **P<0.01 vs. DM rats. AAP, Auricularia auricular polysaccharide; CT, control group; DH, metformin group; DM, diabetic model group; HFHSD, high-fat high sucrose diet; IFN-γ, interferon-γ; IL-2, interleukin-2; Met, metformin; NF-κB, nuclear factor-κB; STZ, streptozotocin; TNF-α; tumor necrosis factor-α.