Effects of isoimperatorin on the expression levels of mitochondria-mediated apoptosis-associated proteins. Protein levels of Survivin, Mcl-1, Bcl-xl, Bcl-2, Smac, Bax, c-caspase-9 and c-caspase-3 were examined. *P<0.05 and **P<0.01, compared with the control. Mcl-1, myeloid leukemia cell-1; Bcl-2, B cell lymphoma-2; Bcl-xl, B cell lymphoma-extra large; Smac, second mitochondria-derived activator of caspase; Bax, Bcl-2-associated X factor.