Table 2.
Mean (± SD) SKAMP Total Scores at Each Observation Session for Each Treatment at Each Dose Levela
| MCD | CON | PLA | |||||||
| Observation Session (hrs) | Low | Med | High | Low | Med | High | Low | Med | High |
| 0 | 18.48 (11.82) | 20.88 (12.95) | 19.91 (13.15) | 18.04 (10.13) | 19.14 (12.14) | 21.47 (13.06) | 13.58 (9.72) | 16.02 (11.84) | 13.96 (11.14) |
| 1.5 | 11.44 (7.99) | 10.98 (8.62) | 6.55 (5.85) | 14.04 (9.85) | 14.86 (12.01) | 11.34 (9.71) | 19.10 (12.83) | 19.47 (12.56) | 18.88 (13.48) |
| 3.0 | 12.57 (9.92) | 11.03 (9.66) | 7.31 (6.10) | 16.44 (12.43) | 15.29 (12.72) | 12.62 (11.00) | 21.47 (14.61) | 20.98 (14.11) | 22.11 (14.10) |
| 4.5 | 13.46 (11.53) | 12.39 (10.32) | 9.15 (8.62) | 17.55 (13.37) | 15.09 (12.60) | 13.55 (11.91) | 20.23 (11.92) | 22.09 (15.46) | 23.44 (12.55) |
| 6.0 | 16.08 (13.27) | 14.47 (11.53) | 10.30 (9.71) | 17.00 (12.12) | 14.28 (11.73) | 12.04 (11.62) | 22.98 (12.79) | 22.15 (13.91) | 26.02 (14.56) |
| 7.5 | 15.85 (11.21) | 17.26 (13.63) | 14.29 (12.55) | 18.62 (12.66) | 15.19 (13.47) | 13.47 (12.97) | 23.54 (12.96) | 23.13 (14.72) | 24.48 (14.68) |
| 12.0 | 20.44 (13.75) | 20.28 (15.02 | 19.85 (14.41) | 16.90 (13.36) | 17.81 (13.84) | 16.74 (14.98) | 19.45 (13.46) | 20.73 (13.46) | 22.02 (15.17) |
aLower SKAMP scores indicate greater efficacy
CON = Concerta; MCD = Metadate CD; PLA = placebo. Low = Low Dose (CON 18 mg; MCD 20 mg), Med = Medium Dose (CON 36 mg; MCD 40 mg), Hi = High Dose (CON 54 mg ; MCD 60 mg).