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. Author manuscript; available in PMC: 2017 Nov 13.
Published in final edited form as: Pharmacol Biochem Behav. 2016 Nov 13;150-151:198–206. doi: 10.1016/j.pbb.2016.11.003

Fig. 2.

Fig. 2

N-phenylpropyl-N´-substituted piperazine sigma receptor ligands dose-dependently inhibit [125I]E-IA-DM-PE-PIPZE specific binding to σ1 receptors in vivo at 30 min in mouse brain. ED50 values were calculated from sigmoidal logistic fits with bottom plateaus constrained to zero.