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. Author manuscript; available in PMC: 2017 Nov 13.
Published in final edited form as: Pharmacol Biochem Behav. 2016 Nov 13;150-151:198–206. doi: 10.1016/j.pbb.2016.11.003

Fig. 7.

Fig. 7

Nahas-3h attenuates and enhances methamphetamine-induced hyperactivity. Mice were placed in an activity monitor for 45 min, injected (i.p.) with Nahas-3h (3.16 – 31.6 µmol/kg) or saline, returned to the monitor for 15 min, injected (i.p.) with methamphetamine (0.5 mg/kg) or saline, and placed in the monitor for 60 min. Panel A depicts distance traveled (in cm) summed across the 60-min period after methamphetamine or saline injection. The asterisk designates a significant (p < 0.05, Tukey post-hoc analysis) difference from the group administered saline and methamphetamine. Panels B and C depict distance traveled (in cm) in 5-min intervals. The left arrow designates Nahas-3h or saline injection and the right arrow designates methamphetamine or saline injection. Asterisks designate a significant (p < 0.05, Tukey post-hoc analysis) difference from the group administered saline and methamphetamine at the respective time point.