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. 2016 Dec 1;13(1):63–68. doi: 10.3892/etm.2016.3940

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Copyright: © Qing et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Synovial fluid levels of HIF-1α are correlated with the KL grade of osteoarthritis (Spearman's ρ=0.933; P<0.001). Disease severity was determined via weight-bearing anteroposterior radiographs of the affected knee. Knee radiographs were evaluated according to the KL classification. Spearman's correlation was employed to determine the correlation between synovial fluid levels of HIF-1α and severity of osteoarthritis. HIF-1α, hypoxia-inducible factor 1α; KL, Kellgren and Lawrence; OA, osteoarthritis.