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. Author manuscript; available in PMC: 2017 Jan 19.
Published in final edited form as: Andrology. 2016 Mar 22;4(4):565–572. doi: 10.1111/andr.12178

Table 2.

Country-specific estimates of attributable costs (base case scenarios for individual exposure-outcome relationships without accounting for probability of causation). Estimates not rounded for significant digits

Country Polybrominated
diphenyl ether
and lost cognition
Organophosphate
and lost cognition
Autism ADHD DDE-Childhood obesity DDE-Adult diabetes Phthalate-adult obesity Phthalate-adult diabetes Bisphenol A-childhood obesity Testicular cancer
Austria € 176,283,397 € 2,590,556,536 € 3,712,201 € 36,402,871 € 457,864 € 18,576,326 € 174,436,546 € 13,506,936 € 28,626,042 € 21,542,193
Belgium € 272,153,094 € 4,147,634,011 € 5,652,233 € 47,389,400 € 462,242 € 22,770,259 € 235,409,768 € 16,556,365 € 43,586,286 € 16,701,009
Bulgaria € 57,786,610 € 875,407,110 € 1,139,288 € 9,162,154 € 117,297 € 4,151,953 € 186,303,727 € 3,018,905 € 8,785,434 € 4,179,805
Croatia € 48,825,603 € 756,198,808 € 934,887 € 9,228,661 € 117,260 € 3,245,031 € 100,589,057 € 2,359,478 € 7,209,231 € 4,510,408
Cyprus € 16,218,595 € 245,788,264 € 341,588 € 3,207,904 € 73,697 € 816,057 € 17,883,719 € 593,359 € 2,634,104 € 1,095,216
Czech Republic € 165,306,044 € 2,515,515,985 € 3,443,213 € 23,601,599 € 313,514 € 11,458,530 € 286,218,431 € 8,331,553 € 26,551,785 € 17,873,104
Denmark € 141,562,301 € 2,155,440,588 € 3,103,908 € 28,629,357 € 177,290 € 12,121,072 € 120,825,618 € 8,813,290 € 23,935,286 € 20,510,714
Estonia € 17,616,470 € 267,739,108 € 365,573 € 2,510,613 € 22,958 € 795,900 € 29,182,923 € 578,703 € 2,819,059 € 808,371
Finland € 121,526,668 € 1,849,790,532 € 2,535,114 € 22,151,271 € 225,306 € 9,616,215 € 138,122,297 € 6,991,996 € 19,549,124 € 5,650,974
France € 1,605,895,077 € 24,520,883,006 € 32,323,890 € 280,421,576 € 2,519,325 € 144,565,573 € 1,335,656,554 € 105,114,327 € 249,260,491 € 127,456,361
Germany € 1,441,817,385 € 22,022,914,292 € 30,118,102 € 306,324,578 € 3,754,568 € 173,822,899 € 1,932,811,050 € 126,387,471 € 232,250,909 € 212,806,020
Greece € 180,731,574 € 2,760,253,146 € 3,598,297 € 30,612,497 € 806,412 € 20,697,296 € 221,936,290 € 15,049,104 € 27,747,692 € 5,383,183
Hungary € 104,043,559 € 1,583,806,141 € 2,344,763 € 21,053,456 € 339,787 € 9,929,408 € 253,747,009 € 7,219,720 € 18,081,265 € 18,447,596
Ireland € 169,313,689 € 2,579,727,151 € 3,445,815 € 25,237,233 € 391,114 € 9,172,269 € 95,779,768 € 6,669,201 € 26,571,853 € 13,312,897
Italy € 1,035,810,634 € 15,790,856,085 € 21,040,159 € 182,641,955 € 4,213,512 € 95,025,679 € 1,222,640,306 € 69,093,631 € 162,247,806 € 108,384,791
Latvia € 18,777,121 € 285,300,786 € 424,250 € 3,075,683 € 30,001 € 1,240,469 € 54,692,920 € 901,951 € 3,271,540 € 1,349,601
Lithuania € 32,439,160 € 492,752,218 € 640,601 € 6,600,704 € 68,408 € 1,856,527 € 71,605,012 € 1,349,890 € 4,939,893 € 889,257
Luxembourg € 26,604,443 € 404,123,792 € 568,011 € 5,286,611 € 42,406 € 1,858,652 € 11,461,322 € 1,351,435 € 4,380,126 € 2,898,370
Malta € 5,654,988 € 86,051,306 € 122,349 € 1,277,233 € 28,277 € 585,445 € 12,361,119 € 425,680 € 943,477 € 661,638
the Netherlands € 420,667,263 € 6,411,680,600 € 9,008,828 € 84,575,295 € 873,804 € 39,846,695 € 394,575,308 € 28,972,725 € 69,470,129 € 43,591,257
Poland € 457,606,139 € 6,961,657,095 € 9,452,137 € 82,801,179 € 1,171,629 € 26,243,313 € 992,691,706 € 19,081,640 € 72,888,639 € 23,907,690
Portugal € 144,471,499 € 2,203,603,758 € 3,037,311 € 29,346,513 € 528,244 € 14,309,316 € 255,357,449 € 10,404,373 € 23,421,739 € 10,479,779
Romania € 184,060,570 € 2,790,833,829 € 3,800,679 € 32,858,172 € 498,677 € 7,800,822 € 458,219,793 € 5,672,015 € 29,308,327 € 8,296,996
Slovakia € 77,460,017 € 1,175,647,445 € 1,530,512 € 13,731,533 € 148,479 € 4,828,094 € 136,980,343 € 3,510,531 € 11,802,295 € 9,778,602
Slovenia € 33,210,579 € 506,653,683 € 650,272 € 5,096,618 € 88,633 € 6,988,227 € 55,914,570 € 5,081,174 € 5,014,468 € 4,296,797
Spain € 840,297,605 € 12,827,278,745 € 18,453,656 € 138,875,274 € 2,753,774 € 62,327,019 € 1,048,621,553 € 45,318,277 € 142,302,406 € 31,817,919
Sweden € 252,752,260 € 3,857,134,138 € 5,113,674 € 39,681,811 € 464,728 € 18,980,390 € 198,227,073 € 13,800,733 € 39,433,274 € 18,845,534
United Kingdom € 1,538,679,076 € 23,513,328,407 € 32,438,565 € 271,550,933 € 3,920,836 € 111,111,733 € 1,548,769,812 € 80,789,878 € 250,144,786 € 112,499,848
Total € 9,587,571,420 € 146,178,556,566 € 199,339,876 € 1,743,332,686 € 24,610,041 € 834,741,170 € 15,416,057,989 € 606,944,344 € 1,537,177,463 € 847,975,932
Country Cryptorchidism Assisted
reproductive
technology
Low testosterone-
induced
early mortality
Fibroids Endometriosis Total (before accounting for probability of causation) Total (after accounting for probability of causation) % GDP Cost per capita, €
Austria € 2,417,333 € 153,452,307 € 113,500,763 € 3,484,157 € 26,717,649 € 3,363,673,122 € 2,874,928,346 1.08% 343
Belgium € 3,680,655 € 87,742,555 € 168,484,239 € 4,059,103 € 31,072,568 € 5,103,353,787 € 4,361,831,821 1.32% 400
Bulgaria € 741,888 € 133,659,875 € 217,087,827 € 1,021,780 € 8,109,474 € 1,510,673,128 € 1,291,170,943 1.56% 171
Croatia € 608,785 a € 97,246,170 € 792,830 € 6,054,072 € 1,037,920,281 € 887,109,516 1.39% 201
Cyprus € 222,438 a € 9,871,143 € 291,515 € 2,362,613 € 301,400,214 € 257,606,487 1.20% 233
Czech Republic € 2,242,172 € 110,747,866 € 230,138,669 € 2,674,149 € 21,908,503 € 3,426,325,115 € 2,928,476,947 1.35% 278
Denmark € 2,021,221 € 41,430,280 € 89,799,344 € 2,163,016 € 16,517,999 € 2,667,051,283 € 2,279,526,296 1.29% 411
Estonia € 238,056 € 15,810,248 € 34,033,247 € 271,982 € 2,132,452 € 374,925,664 € 320,448,622 1.50% 239
Finland € 1,650,831 € 49,222,355 € 96,278,892 € 1,808,061 € 13,534,842 € 2,338,654,479 € 1,998,845,848 1.27% 373
France € 21,048,863 € 490,225,873 € 911,131,192 € 16,676,199 € 166,119,437 € 30,009,297,745 € 25,648,919,380 1.44% 394
Germany € 19,612,485 € 841,617,666 € 1,154,884,577 € 36,077,846 € 225,556,846 € 28,760,756,694 € 24,581,792,484 1.00% 301
Greece € 2,343,161 € 105,442,866 € 148,392,948 € 3,077,791 € 24,822,320 € 3,550,894,577 € 3,034,946,353 1.23% 268
Hungary € 1,526,877 € 81,451,884 € 272,285,970 € 2,085,162 € 16,838,619 € 2,393,201,217 € 2,045,466,894 1.25% 205
Ireland € 2,243,867 € 50,774,130 € 49,629,926 € 2,016,420 € 16,939,853 € 3,051,225,187 € 2,607,879,381 1.75% 583
Italy € 13,701,056 € 785,378,265 € 761,262,535 € 18,662,064 € 146,003,504 € 20,416,961,981 € 17,450,358,761 1.11% 289
Latvia € 276,266 € 24,513,583 € 56,256,708 € 360,634 € 2,768,583 € 453,240,096 € 387,383,897 1.37% 173
Lithuania € 417,150 € 82,118,157 € 81,428,005 € 607,233 € 4,508,762 € 782,220,977 € 668,563,555 1.41% 203
Luxembourg € 369,881 a € 6,274,862 € 443,381 € 3,511,401 € 469,174,695 € 401,003,184 1.23% 791
Malta € 79,672 € 2,357,141 € 6,035,588 € 109,790 € 843,807 € 117,537,510 € 100,459,202 1.11% 241
the Netherlands € 5,866,422 € 194,833,360 € 233,504,691 € 6,832,430 € 51,876,133 € 7,996,174,939 € 6,834,323,419 1.20% 411
Poland € 6,155,099 a € 909,890,170 € 8,189,650 € 64,950,534 € 9,636,686,621 € 8,236,467,256 1.37% 216
Portugal € 1,977,854 € 63,958,781 € 166,084,045 € 2,746,572 € 21,737,524 € 2,951,464,756 € 2,522,614,232 1.16% 237
Romania € 2,474,949 € 281,779,421 € 539,300,178 € 3,186,497 € 26,208,342 € 4,374,299,266 € 3,738,709,588 1.46% 174
Slovakia € 996,648 € 40,988,960 € 130,706,244 € 1,355,626 € 10,847,532 € 1,620,312,859 € 1,384,879,921 3.21% 255
Slovenia € 423,448 € 16,365,189 € 36,061,381 € 544,843 € 4,292,432 € 680,682,315 € 581,778,553 0.58% 284
Spain € 12,016,761 € 590,471,638 € 534,315,007 € 15,208,873 € 125,288,191 € 16,435,346,696 € 14,047,275,813 1.22% 305
Sweden € 3,329,952 € 75,804,018 € 120,986,094 € 3,496,078 € 27,069,183 € 4,675,118,939 € 3,995,819,888 1.34% 426
United Kingdom € 21,123,538 € 374,944,603 € 783,487,823 € 24,881,563 € 177,011,900 € 28,844,683,301 € 24,653,524,478 1.43% 396
Total € 129,807,327 € 4,714,114,146 € 7,958,358,238 € 163,125,243 € 1,245,605,077 € 191,187,317,516 € 163,407,625,697 1.28% 322
a

Data not available to evaluate phthalate-attributable ART costs in these countries.