Table III.

Multivariate analyses for RFS and OS in pediatric ALL patients.

	RFS			OS
Factor	HR	95% CI	P-value	HR	95% CI	P-value
Age, ≤1 year, ≥10 years vs. 1–10 years	1.67	0.82–3.42	0.157	1.83	0.87–3.84	0.109
WBC, ≥50×109/l vs. <50×109/l	1.75	0.86–3.59	0.125	2.19	1.05–4.57	0.036
Risk, high vs. low + intermediate	1.77	0.88–3.55	0.108	1.72	0.83–3.59	0.146
ERG expression, low vs. high	2.17	1.05–4.48	0.036	1.21	0.58–2.50	0.624
BM blast %, ≥median vs. <median	2.47	1.13–5.38	0.023	2.87	1.22–6.73	0.015
BCR/ABL1, presence vs. absence	3.41	1.38–8.42	0.008	2.19	0.82–5.88	0.119

ALL, acute lymphoblastic leukemia; OS, overall survival; RFS, relapse-free survival; ERG, ETS-related gene; WBC, white blood cell; BM, bone marrow; BCR/ABL1, breakpoint cluster region/Abelson murine leukemia viral oncogene homolog 1; HR, hazard ratio; CI, confidence interval.