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. 2016 Dec 1;13(1):79–84. doi: 10.3892/etm.2016.3942

Figure 1.

Figure 1.

Silencing of miR-376b inhibits 4T1 cell migration and invasion. (A) miR-376b expression was detected in normal breast tissue from mice and JC and 4T1 breast cancer cells using quantitative polymerase chain reaction (qPCR; n=3; **P<0.01). (B) miR-376b expression in 4T1 cells after transfection with miR-NC and miR-376b-mimic for 48 h was detected by qPCR (n=3; **P<0.01). (C) Transwell migration assay of 4T1 cells that were transfected with miR-NC or miR-376b-mimic. The migrated cells per field were analyzed (n=6). (D) Transwell-based matrigel invasion assay of 4T1 cells that were transfected with miR-NC or miR-376b-mimic. The invaded cells per field were analyzed (n=6). miR, microRNA; NC, normal control.