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. 2016 Dec 1;13(1):79–84. doi: 10.3892/etm.2016.3942

Figure 3.

Figure 3.

Silencing of miR-376b inhibits 4T1 cell metastasis in mice. (A) Survival percent of the mice intravenous injected with miR-NC or miR-376b-mimic transfected 4T1 cells (n=10; P<0.0001). (B) Bright imaging of the lungs from 4T1 bearing mice. (C) Hematoxylin and eosin staining was used to test the metastasis of the lungs (magnification, ×200). Arrows indicate lung metastasis. (D and E) Number of visible lung metastases and tumor area in lungs in 4T1-bearing mice (miR-NC or miR-376b-mimic transfected 4T1 cells; n=5, P=0.001). miR, microRNA; NC, normal control.