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. Author manuscript; available in PMC: 2017 Jan 19.
Published in final edited form as: Dev Dyn. 2014 May 10;243(8):965–976. doi: 10.1002/dvdy.24139

Figure 1.

Figure 1

The genomic organization of the pnc-1 locus showing intron-exon structure and promoter regions. The constructs used in this study are also diagrammed. The location of the point mutation in pnc-1(pk9605) is indicated by an open arrowhead. The red star indicates the mutated signal sequence in pnc-1 ΔSS. Solid boxes and right pointing arrows represent coding regions and promoters, respectively. The 1a exon contains the first 17 signal sequence amino acids and the 1b exon the remaining three signal sequence amino acids and cleavage site. In all other respects, PNC-1 expressed from the three promoters is identical.