Figure 2.
Future and or ongoing areas of investigation for therapeutic hypothermia in neurocritical care including traumatic brain injury, cardiac arrest in children and adults, perinatal asphyxia, spinal cord injury, stroke, refractory status epilepticus, and trauma induced exsanguination cardiac arrest. RCTs = randomized controlled trials, TTM = targeted temperature management, HIE = hypoxic ischemic encephalopathy, EPR = emergency preservation and resuscitation, CAT = cardiac arrest from trauma.