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. 2016 Oct 20;6(10):189. doi: 10.3390/nano6100189

Figure 4.

Figure 4

Effects of Ag NPs/CNFS removal and washing on wound epithelialization. Ag NPs/CNFS (◇) and CNFS (○) were removed, and Ag NPs/CNFS was removed and the wound was washed with saline (□) on the indicated day after wound creation, and digital photographs were taken to quantify the epithelialization rates (A and B). Each photograph was representative of six wounds (A). Data represent the mean ± SD of 6 determinations, Wilcoxon rank sum test (multiple comparison), * p < 0.05, ** p < 0.01 (B). Wound closure in the wash group was recovered by removal of Ag NPs/CNFS on day 4–9. Histological examination of reepithelialization and granulation of wounds treated with Ag NPs/CNFS on days 2 and 4, and each microphotograph was representative of six cultures (C).