Table 1.
Summary of the correlation analysis between IGF-1, Shh, HGF expression in KPC and orthotopic mouse models of PDAC.
| Mouse # | IGF-1 | Shh | HGF | |
|---|---|---|---|---|
| Orthotopic | 632 | Low | High | Low |
| 679 | Low | Low | High | |
| 633 | High | High | Low | |
| 678 | Low | High | High | |
| 638 | High | High | Low | |
| 634 | Low | Low | High | |
| 680 | High | High | Low | |
| KPC | 432 | High | High | Low |
| 7767 | Low | Low | High | |
| 1000 | Low | Low | High | |
| 9082 | Low | Low | High | |
| 0121 | Low | Low | High | |
| 7772 | Low | Low | High | |
| 9066 | High | High | Low |
Correlation between IGF-1/Shh (all mice) and Shh/HGF (all mice) of IHC scoring was performed and phi (ϕ) coefficients were calculated.IGF1/Shh (ϕ=0.7454 and **p<0.01) and Shh/HGF (ϕ=-0.8660 and **** p<0.0001).