Table 2. Base case analysis of competing strategies for the management of second recurrence of community-onset Clostridium difficile infection.

Treatment	Cost (€)	QALY	ICER
Vancomycin pulse/taper	1235	0.1812
Fidaxomicin	2464	0.1988	(Dominated)
FMT via duodenal infusion	1834	0.2013	(Dominated)
FMT via enema	1610	0.2019	18,092a
FMT via colonoscopy	1816	0.2047	73,653b

Abbreviations: FMT: fecal microbiota transplantation; ICER: incremental cost-effectiveness ratio; QALY: quality-adjusted life year. Costs values are reported as 2016 Euros.

^aICER calculated for FMT via enema relative to pulsed-tapered vancomycin.

^bICER calculated for FMT via colonoscopy relative to FMT via enema.