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. 2017 Jan 19;12(1):e0169894. doi: 10.1371/journal.pone.0169894

Table 2. Unique genes differentially expressed during Incipient CLAD vs. No CLAD.

Gene Name Gene Symbol (GenBank Acc) FC P-value
Down-regulated genes
--- (BG389789) -4.51 0.017
egf-like module containing, mucin-like, hormone receptor-like 1 EMR1 -2.53 0.015
--- (H78083) -2.24 0.017
fibronectin type III domain containing 3B FNDC3B -2.07 0.037
Up-regulated genes
chemokine (C-X-C motif) ligand 13 CXCL13 5.48 0.009
hemoglobin, alpha 1 /// hemoglobin, alpha 2 HBA1 /// HBA2 5.31 0.014
hemoglobin, beta HBB 4.41 0.021
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) GZMA 3.33 0.011
granzyme H (cathepsin G-like 2, protein h-CCPX) GZMH 2.96 0.007
T cell receptor beta constant 1 TRBC1 2.86 0.029
B-cell CLL/lymphoma 11B (zinc finger protein) BCL11B 2.79 0.017
chemokine (C-C motif) ligand 5 CCL5 2.67 0.046
CD8a molecule CD8A 2.58 0.017
perforin 1 (pore forming protein) PRF1 2.55 0.014
regulator of G-protein signaling 1 RGS1 2.48 0.021
LCK proto-oncogene, Src family tyrosine kinase LCK 2.47 0.032
granulysin GNLY 2.45 0.041
NLR family, CARD domain containing 3 NLRC3 2.42 0.029
--- (AI949912) 2.37 0.004
HOP homeobox HOPX 2.35 0.016
ADP-ribosylation factor-like 4C ARL4C 2.33 0.034
killer cell lectin-like receptor subfamily C, member 1, member 2 KLRC1 /// KLRC2 2.32 0.038
microRNA 6883 /// period circadian clock 1 PER1 2.31 0.001
killer cell lectin-like receptor subfamily K, member 1 KLRK1 2.31 0.031
eomesodermin EOMES 2.30 0.010
natural killer cell granule protein 7 NKG7 2.29 0.036
--- (AI475680) 2.25 0.017
tripartite motif containing 58 TRIM58 2.24 0.033
annexin A1 ANXA1 2.23 0.036
B-cell translocation gene 1, anti-proliferative BTG1 2.19 0.011
killer cell lectin-like receptor subfamily D, member 1 KLRD1 2.17 0.011
plastin 3 PLS3 2.14 0.029
--- RP11-489E7.4 2.13 0.016
ATPase, aminophospholipid transporter, class I, type 8B, member 2 ATP8B2 2.11 0.049
cytotoxic T-lymphocyte-associated protein 4 CTLA4 2.08 0.047
synuclein, alpha (non A4 component of amyloid precursor) SNCA 2.05 0.014
chloride intracellular channel 3 CLIC3 2.05 0.020
killer cell lectin-like receptor subfamily B, member 1 KLRB1 2.04 0.035
transmembrane protein 200A TMEM200A 2.04 0.039
sterile alpha motif domain containing 3 SAMD3 2.01 0.017