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. 2017 Jan 19;12(1):e0169496. doi: 10.1371/journal.pone.0169496

Fig 4. Chemokine receptor and ligand mRNA expression in hamster spleen tissue over the course of chronic L. donovani infection.

Fig 4

mRNA expression of type 1, type 2 and regulatory type chemokine ligands and their receptors was determined by real time RT-PCR in spleen tissue from uninfected controls (C) or hamsters infected for 7, 14, 21 and 28 days. Results are expressed as a relative fold-increase between experimental samples and uninfected BHK cells. Shown is the mean and SEM of a single experiment representative of 2 independent experiments from 3–6 hamsters per time point. *p<0.05; **p<0.01, ***p<0.001. Th1-associated genes indicated by the color red, Th2/Treg-associated genes indicated by the color black, Th1/Th2-associated genes indicated by the color blue.