Table 1. Upregulated genes related to T cell activation and function a.
| Gene Symbol | Protein Name | FC c |
|---|---|---|
| IFNG | Interferon gamma | 52.2 |
| LAG3 b | Lymphocyte activation gene 3 | 27.3 |
| PDCD1LG2 b | Programmed cell death 1 ligand 2 | 26.9 |
| CCR5 | C-C chemokine receptor 5 | 19.8 |
| TNFRSF4 | OX40, Tumor necrosis factor receptor superfamily member 4 | 9.7 |
| CTLA4 b | Cytotoxic T-lymphocyte associated protein 4 | 7.5 |
| TNF | Tumor necrosis factor alpha | 6.8 |
| IL12RB2 | Interleukin 12 receptor subunit beta 2 | 4.8 |
| CXCR3 | C-X-C chemokine receptor 3 | 3.6 |
| PDCD1 b | Programmed cell death 1 | 3.3 |
| TNFRSF9 | CD137, Tumor necrosis factor receptor superfamily member 9 | 3.1 |
| TBX21 | Tbet, T-box transcription factor 21 | 3.0 |
| PTPRC | CD45 antigen, protein tyrosine phosphatase receptor type c | 2.7 |
| TNFRSF14 | CD270, Tumor necrosis factor receptor superfamily member 14 | 2.6 |
| CD274 b | Programmed cell death 1 ligand 1 | 2.6 |
| CD44 | CD44 antigen | 2.4 |
| IL2RB | Interleukin 2 receptor subunit beta | 2.0 |
| CD4 | Cluster of differentiation 4 | 1.6 |
a Manually curated list; False Discovery rate <0.01
b Inhibitory receptors
c Fold-change