Table 1. Baseline clinical characteristics.
| Clinical features | Female | Male |
|---|---|---|
| Patients | 295 (78.67%) | 52 (21.33%) |
| Age, mean ± SD (Years) | 60.95 ± 12.88 | 61.22 ± 16.39 |
| ACR classificative criteria 1987 | 64.70% | 73.10% |
| ACR/EULAR classificative criteria 2010 | 99.70% | 98.1% |
| Disease duration (mean ± SD) | 11.75 ± 7.01 | 11.01 ± 7.69 |
| < 1 years | 3.10% | 5.80% |
| between 1 and 5 years | 25.40% | 25.00% |
| between 5 and 10 years | 22.40% | 30.82% |
| ≥ 10 years | 49.20% | 38.53% |
| RF and/or ACPA | 70.50% | 71.22% |
| WBC (103/mL) (mean ± SD) | 5.61 ± 1.28 | 5.52 ± 1.36 |
| RBC (103/mL) (mean ± SD) | 4.87 ± 0.54 | 4.85 ± 0.68 |
| PLT (103/mL) (mean ± SD) | 238.28 ± 28.41 | 251.26 ± 31.01 |
| Radiologic damage | 24.09% | 15.41% |
| Joint surgery | 6.40% | 7.80% |
| Extra-articular disease | 14.6% | 19.20% |
| Pulmonary fibrosis | 4.43% | 4.50% |
| Sjogren’s Syndrome | 2.01% | 2.02% |
| Rheumatoid Vasculitis | 0.44% | 1.00% |
| Disease activity_DAS28_Time 0 (mean ± SD) | 4.09 ± 1.01 | 4.69 ± 1.04 |
| Remission | 0.71% | 2.00& |
| Low disease activity | 1.39% | 0% |
| Moderate disease activity | 58.60% | 58.80% |
| High disease activity | 6.80% | 39.20% |
| SDAI_ Time 0 (mean ± SD) | 24.21 ± 7.57 | 25.35 ± 8.87 |
| HAQ-DI_ Time 0 (mean ± SD) | 0.97 ± 0.64 | 0.68 ± 0.53 |
| Smoke | 27.11% | 68.81% |
| BMI | ||
| <18.49 | 4.69% | 1.90% |
| >18.5 <24.99 | 60.71% | 69.20% |
| >25 <29.99 | 27.82% | 38.50% |
| >30 | 6.78% | 0% |
| Familiarity_CVEs | 34.50% | 30.40% |
| Systemic Arterial Hypertension | 43.09% | 38.50% |
| Systolic blood pressure (mmHg) (mean ± SD) | 128.31 ± 21.05 | 119.21 ± 10.11 |
| Dystolic blood pressure (mmHg) (mean ± SD) | 81.35 ± 4.23 | 79.39 ± 08.51 |
| Heart rate (Beat/min) (mean ± SD) | 71.32 ± 9.12 | 74.71 ± 7.95 |
| Type 2 diabetes | 10.81% | 13.50% |
| Metabolic syndrome | 32.50% | 11.50% |
| Cholesterol mg/dl | 196.41 ± 55.25 | 179.90 ± 56.21 |
| Cholesterol>200 mg/dl | 47.45% | 30.76% |
| Tryglycerides mg/dl | 116.98 ± 44.59 | 109.28 ± 37.71 |
| Glycemia mg/dl | 93.08 ± 17.24 | 88.25 ± 14.04 |
| Glycemia >110 mg/dl | 14.57% | 21.15% |
Abbreviations: RF: rheumatoid factor; ACPA: Anti–citrullinated protein antibody; WBC: white blood cell count; RBC: red blood cells; HB: hemoglobin; PLT: platelet count; DAS28: Disease Activity Score in 28 joints; SDAI: simplified disease activity index; HAQ-DI: health assessment questionnaire disability Index; BMI: body mass index, CV: cardiovascular, CVEs: cerebro-cardiovascular events.