Table 2. Mean comparison of gene expression between controls and AML patients.
| Series 1 | Series 2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Controls | AML patients | Mann-Whitney | Controls | AML patients | Mann-Whitney | |||||
| n | Mean$ (SE) | n | Mean$ (SE) | P-value# | n | Mean$ (SE) | n | Mean$ (SE) | P-value# | |
| C-Myc | 7 | 2.233 (0.41) | 21 | 4.165 (0.30) | 0.0058** | 7 | 2.233 (0.41) | 20 | 6.883 (0.51) | 0.0004*** |
| NPM1 | 8 | 1.418 (0.93) | 32 | 3.213 (0.42) | 0.0759 | 8 | 1.418 (0.93) | 75 | 9.900 (0.50) | < 0.0001*** |
| 18S | 8 | 0.341 (0.41) | 25 | 0.888 (0.31) | 0.1722 | 8 | 0.341 (0.41) | 34 | 2.833 (0.28) | 0.0007*** |
| NCL | 9 | 1.372 (0.60) | 25 | 2.944 (0.34) | 0.0386* | 9 | 1.372 (0.60) | 90 | 7.474 (0.41) | < 0.0001*** |
| FBL | 8 | 2.029 (0.65) | 31 | 3.257 (0.27) | 0.0536 | 8 | 2.029 (0.65) | 84 | 1.883 (0.18) | 0.8789 |
| Nop58 | 8 | 1.535 (0.63) | 15 | 3.860 (0.53) | 0.0155* | na | na | na | na | na |
| Nop56 | 8 | 2.571 (0.78) | 28 | 4.241 (0.38) | 0.0316* | 8 | 2.571 (0.78) | 98 | 10.07 (0.40) | < 0.0001*** |
| NHP2L1 | 5 | -1.35 (2.27) | 16 | 1.678 (0.58) | 0.0759 | 5 | -1.35 (2.27) | 90 | 1.929 (0.16) | 0.0105* |
$ Mean value: log2(fold-change);
# Two-tailed P-value; ns: no significant; na: not available
*: P-value < 0.05;
**: P-value < 0.01;
***: P-value < 0.001