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. 2017 Jan 19;12(1):e0170277. doi: 10.1371/journal.pone.0170277

Table 3. Comparison of age-adjusted mean differences in the scores before and after the intervention in the three groups.

Treatment group Mean Difference
Item Honey 1 (G1) (n = 42) Honey 2 (G2) (n = 25) Diphenhydramine (G3) (n = 20) P a G1 vs. G2 b G1 vs. G3 G2 vs. G3
Cough frequency 1.4±1.3 1.9±1.9 0.9±1.0 0.071 -0.5 0.5 1.0c
Cough severity 1.7±1.2 2.2±1.7 0.7±0.9 0.002 -0.5 1.0c 1.5d
Bothersome nature of cough 1.7±1.2 2.0±1.9 0.6±0.9 0.006 -0.4 1.0c 1.4c
Sleep quality in child 2.2±1.6 1.8±2.3 0.9±1.0 0.057 0.3 1.2c 0.8
Sleep quality in parents 2.1±1.3 2.2±1.4 1.0±1.0 0.003 -0.1 1.1c 1.2c
Combined 9.1±6.1 10.2±9.2 4.2±4.5 0.011 -1.2 4.8c 6.0c

Data are presented as mean±SD.

a Analysis of variance;

b Post hoc multiple comparisons by LSD.

c P< 0.050;

d P< 0.001.