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. 2016 Dec 23;5:e17197. doi: 10.7554/eLife.17197

Figure 6. Reopening the critical period for visual and auditory imprinting through eIF2α.

Figure 6.

(a) Chickens were trained 4 days after hatching (P4) and tested 24 hr after training. To target translational control by eIF2α, chickens were injected with PKRi or ISRIB. (b) Controls injected with vehicle (n = 12) did not show auditory imprinting at P4 but the critical period in animals treated with PKRi (n = 13) or ISRIB (n = 13) was reopened. (c) Visual imprinting was not restored in chickens injected with PKRi (n = 13) and ISRIB (n = 13) or injected with vehicle (n = 12). * indicates p<0.05 from two-ways ANOVA test, Bonferroni Post hoc test.

DOI: http://dx.doi.org/10.7554/eLife.17197.015

Figure 6—source data 1. Preference indexes of animals trained in P4 and injected with PKRi, ISRIB or vehicle.
DOI: http://dx.doi.org/10.7554/eLife.17197.016
elife-17197-fig6-data1.xlsx (12.8KB, xlsx)
DOI: 10.7554/eLife.17197.016