Table 3.
MIC of antibiotics against fox AmpC and ESBL-producing isolates
| Antibiotics | AmpC | AmpC + ESBL | AmpC | AmpC + ESBL | P-value | AmpC | AmpC + ESBL | AmpC | AmpC + ESBL | P-value |
|---|---|---|---|---|---|---|---|---|---|---|
|
|
|
|
|
|||||||
| Salmonella choleraesuis | Salmonella enteritidis | Salmonella typhimurium | Salmonella typhi | |||||||
| LAEV | 0.19 (0.12–0.25) | ND | 0.19 (0.12–0.5) | 0.2 (0.12–0.25) | >0.05 | 0.47 (0.12–1.0) | ND | 0.77 (0.12–2.0) | 1.07 (0.5–2.0) | >0.05 |
| IMP | 0.18 (0.25–0.5) | ND | 0.42 (0.25–0.5) | 0.42 (0.25–0.5) | >0.05 | 0.56 (0.25–1.0) | ND | 0.71 (0.25–2.0) | 1.07 (0.5–2.0) | >0.05 |
| COT | 8.5 (4–16) | ND | 8 (4–16) | 13.3 (8–16) | >0.05 | 10 (4–16) | ND | 9.7 (4–16) | 11.4 (4–16) | >0.05 |
| GEN | 1.5 (1–2) | ND | 2.3 (1–4) | 3.3 (2–4) | >0.05 | 2.75 (1–4) | ND | 3 (1–4) | 3.4 (1–4) | >0.05 |
| CAZ | 6 (4–8) | ND | 5.3 (4–8) | 13.3 (8–16) | <0.05 | 4.5 (2–8) | ND | 7.1 (2–16) | 19.4 (8–32) | <0.05 |
Notes: MIC, mean (range), μg/mL. Difference in mean MIC values between AmpC + ESBL versus AmpC alone was analyzed by Student’s t-test. P<0.05 was considered to be significant.
Abbreviations: CAZ, ceftazidime; COT, cotrimoxazole; ESBL, extended-spectrum β-lactamase; GEN, gentamicin; IMP, imipenem; LAEV, levofloxacin; MIC, minimum inhibitory concentration; ND, not determined.