Fig. 3.
Intestinal barrier function in NEC. The intestinal mucosal tissues were mounted on Ussing chambers as described in methods to measure transepithelial electrical resistance (TER). The NEC margin and NEC affected tissue had significantly lower TER compared to control tissue. Control groups were then stratified by weight (A) and corrected gestational age (B). Tissues from more preterm, lower birth-weight infants had lower TER compared to tissues from infants that were more mature (*, #, p < 0.01 vs. control, n ≥ 3).