Table 3.
Analysis of genotypes of CD44rs4755392 A/T, CD44rs187115 C/T, CD44rs13347 C/T, CD44 rs353639 G/T and CD44rs187116 A/G on the basis of smoking among bladder cancer patients
| Genotype | Patients non smokers n = 48 [n (%)] |
Patients smoker n = 116 [n (%)] |
p value | OR* (95 % CI) |
|---|---|---|---|---|
| CD44rs4755392 A/T | ||||
| AA | 19 (39.6) | 39 (33.6) | Ref | Ref |
| AT | 21 (43.8) | 60 (51.7) | 0.381 | 1.392 (0.664–2.917) |
| TT | 8 (16.7) | 17 (14.7) | 0.946 | 1.035 (0.380–2.824) |
| CD44rs187115 C/T | ||||
| CC | 14 (29.2) | 55 (47.4) | Ref | Ref |
| CT | 25 (52.1) | 43 (37.1) | 0.035 | 0.438 (0.203–0.942) |
| TT | 9 (18.8) | 18 (15.5) | 0.182 | 0.509 (0.189–1.373) |
| CD44rs13347 C/T | ||||
| CC | 30 (62.5) | 73 (62.9) | Ref | Ref |
| CT | 13 (27.1) | 37 (31.9) | 0.687 | 1.170 (0.546–2.505) |
| TT | 5 (10.4) | 6 (5.2) | 0.272 | 0.493 (0.140–1.740) |
| CD44rs353639 G/T | ||||
| GG | 28 (58.3) | 50 (43.1) | Ref | Ref |
| GT | 19 (39.6) | 50 (43.1) | 0.279 | 1.474 (0.730–2.974) |
| TT | 1 (2.1) | 16 (13.8) | 0.038 | 1.960 (1.128–3.190) |
| CD44rs187116 A/G | ||||
| AA | 16 (33.3) | 38 (32.8) | Ref | Ref |
| AG | 24 (50.0) | 57 (49.1) | 1.000 | 1.000 (0.470–2.126) |
| GG | 8 (16.7) | 21 (18.1) | 0.845 | 1.105 (0.406–3.011) |
OR odds ratio, CI confidence interval
The statistically significant values are shown in bold