Table 2.

Unadjusted Mean ± SD Protein Levels by Ankle-Brachial Index (ABI) Category.

Characteristics	ABI ≤1.0 n = 261	ABI > 1.0 n = 2080	P Valuea
CCL-21, pg/mL	902 ± 293	789 ± 271	< .001
E-cadherin, ng/mL	238 ± 80	222 ± 62	.003
HGF, pg/mL	1,054 ± 260	973 ± 250	< .001
ICAM-1, ng/mL	266 ± 108	258 ± 118	.30
IL-2sr, pg/mL	808 ± 453	707 ± 327	< .001
L-selectin, ng/mL	876 ± 208	895 ± 194	.16
MMP-1, ng/mL	6.2 ± 4.6	5.5 ± 4.1	.02
MMP-2, ng/mL	198 ± 31	195 ± 31	.16
P-selectin, ng/mL	31 ± 9.3	29 ± 9.2	.002
RANTES, pg/mL	4,933 ± 5081	4,211 ± 3,892	.03
SDF-1α, pg/mL	1,982 ± 480	1,935 ± 441	.11
SLPI, pg/mL	49,755 ± 12853	45,775 ± 10,457	< .001
TGFβ-1, pg/mL	4,259 ± 2431	3,911 ± 2,284	.02
TIMP-2, ng/mL	82 ± 12	81 ± 12	.05
VCAM-1, ng/mL	768 ± 222	728 ± 222	.008

Abbreviations: ABI, ankle-brachial index; CCL21, chemokine ligand 21; HGF, hepatocyte growth factor; ICAM-1, intercellular adhesions molecule 1; IL-2SR, interleukin 2 soluble receptor; MMP-1, matrix metalloproteinase 1; MMP-2, matrix metalloproteinase 2; RANTES, regulated on activation normal T cell expressed and secreted; SDF-1α, stromal derived factor 1α; SLPI, secretory leukocyte protease inhibitor; TGFβ-1, transforming growth factor; TIMP-2, tissue inhibitor of metalloproteinases 2; VCAM-1, vascular cell adhesion molecule 1.

^aP Values by t-test or Wilcoxon test as appropriate.