Table 2.
Influences of quorum-sensing systems on the expression of virulence factors in Aeromonas.
| Virulence determinants | Autoinducer system* | Modulation effect | Strains | References | |
|---|---|---|---|---|---|
| Proteases | Metalloproteases, serine proteases | AI-1 | Up-regulation | A. hydrophila AH-1N (WT, ΔahyI and ΔahyR) | Swift et al., 1999 |
| Proteases | A. hydrophila J-1 (WT and ΔahyR) | Bi et al., 2007 | |||
| AsaP1 protease | A. salmonicida subsp. achromogenes Keldur265-87 (WT and ΔasaI) | Schwenteit et al., 2011 | |||
| Metalloproteases | A. hydrophila {A. dhakensis} SSU (WT, ΔahyRI and ΔahyRI/ahyR+) | Khajanchi et al., 2009 | |||
| Hemolysin | Aerolysin/Enterotoxin cytotoxic Act | AI-3 | Up-regulation | A. hydrophila {A. dhakensis} SSU (WT and ΔqseB) | Khajanchi et al., 2012 |
| beta-hemolysin | AI-1 | Down-regulation | A. hydrophila AH-1N (WT, ΔahyI and ΔahyR) | Swift et al., 1999 | |
| hemolysin | Up-regulation | A. hydrophila J-1 (WT and ΔahyR) | Bi et al., 2007 | ||
| Amylase | AI-1 | Up-regulation | A. hydrophila J-1 (WT and ΔahyR) | Bi et al., 2007 | |
| DNase | AI-1 | Up-regulation | A. hydrophila J-1 (WT and ΔahyR) | Bi et al., 2007 | |
| S-layer | AI-1 | Up-regulation | A. hydrophila J-1 (WT and ΔahyR) | Bi et al., 2007 | |
| Brown pigment | AI-1 | Up-regulation | A. salmonicida subsp. achromogenes Keldur265-87 (WT and ΔasaI) | Schwenteit et al., 2011 | |
| Type III secretion system | AI-1 | Up-regulation (transcription) | A. hydrophila {A. piscicola} AH-3 (WT, ΔahyI and ΔahyR) | Vilches et al., 2009 | |
| No effect (AexU production and translocation) | A. hydrophila {A. dhakensis} SSU (WT, ΔahyRI and ΔahyRI/ahyR+) | Khajanchi et al., 2009 | |||
| Type VI secretion system | AI-1 | Up-regulation | A. hydrophila {A. dhakensis} SSU (WT, ΔahyRI and ΔahyRI/ahyR+) | Khajanchi et al., 2009 | |
*
The table described only AI-1 and AI-3 because the role of AI-2 in virulence factors expression is not yet demonstrated.