TABLE 2.

Kinetic parameters extrapolated to 0 m for all FNIII domains studied

FNIII 2C* and FNIII 9C* were fit by a more complex model (Equation 13).

FNII domain	kop	kcl	mop	mcl	ΔG	meq	kchem	KopL
	s−1	s−1	m−1	m−1	kcal mol−1	kcal mol−1 m−1	m−1 s−1
2C*	2.7 × 10−4 (1 × 10−5)	4.8 (0.2)	1.1 (0.008)	−0.65 (0.01)	5.9 (0.04)	−1.1(0.008)	1,700 (2)	3.2 × 10−5 (7 × 10−7)
3C	1.9 × 10−3 (2 × 10−5)	0.55 (0.01)	1.5 (0.007)	−0.78 (0.01)	3.4 (0.01)	−1.4 (0.006)	2,100 (2)
6C	1.3 × 10−5 (1 × 10−7)	0.14 (0.003)	1.5 (0.002)	−0.20 (0.006)	5.6 (0.02)	−1.0 (0.002)	2,200 (2)
7	6.9 × 10−5 (4 × 10−7)	1.4 (0.01)	0.95 (0.001)	−1.2 (0.002)	5.9 (0.007)	−1.3 (0.008)	1,200 (0.3)
9C*	3 × 10−5 (4 × 10−7)	0.015 (0.0003)	1.2 (0.004)	−0.53 (0.006)	3.7 (0.01)	−1.0 (0.004)	12,000 (40)	2.7 × 10−4 (1 × 10−6)
11C	0.016 (2 × 10−4)	0.06 (0.001)	1.8 (0.02)	−0.93 (0.04)	0.78 (0.02)	−1.6 (0.001)	1,400 (2)
12C	2.3 × 10−4 (1 × 10−6)	0.3 (0.005)	1.1 (0.003)	−1.3 (0.006)	4.3 (0.01)	−1.5 (0.003)	3,700 (3)
Irisin	2.1 × 10−3 (1 × 10−5)	1.9 (0.01)	0.72 (0.002)	−1.7 (0.004)	4.1 (0.005)	−1.4 (0.008)	5,200 (5)
TNfn3	6 × 10−3 (1 × 10−4)	0.72 (0.02)	0.55 (0.008)	−2 (0.02)	2.9 (0.02)	−1.5 (0.01)	6,200 (6)