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. 2017 Jan 20;7:41058. doi: 10.1038/srep41058

Figure 7. Schematic drawing of the role of secreted miR-27a in abnormal EC proliferation during hypertension.

Figure 7

Pathologically elevated cyclic stretch increased the secretion of miR-27a, which was transferred from VSMCs to ECs via the VSMC-MPs, subsequently targeted GRK6, and induced EC proliferation.