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. 2017 Jan 20;7:41060. doi: 10.1038/srep41060

Figure 1. Illustration of the suggested pathophysiological pathways mediating the effects of cold spells on SCD.

Figure 1

Potential effect modification by a cardioprotective medication is marked in each pathway. The pathways are discussed further in the main text, and the selected references have been limited to few examples.