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. 2017 Jan 20;7:40968. doi: 10.1038/srep40968

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Effect of intrarectally administered AITC (1%, 0.05 ml) and PYY knockout (PYY^(−/−)) on the mouse grimace scale (ΔMGS) expressed as action units. One-way ANOVA revealed statistically significant differences among the groups (p < 0.001). The data shown are means + SEM, n = 6–7 per group; ***p < 0.001 compared to WT + PO; ^δδδp < 0.001 compared to PYY^(−/−) + PO.