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. 2017 Jan 20;7:40968. doi: 10.1038/srep40968

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Copyright © 2017, The Author(s)

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Mechanical pain threshold (MPT) of the plantar surface of the hindpaws in WT and PYY knockout (PYY^(−/−)) mice before (baseline, A) and after (post-treatment, B) intrarectal administration of PO or AITC (1%, 0.05 ml) and the difference between the two measurements (ΔMPT, C). MPT was assessed with von Frey hairs, and the values represent the average of measurements in both hind paws. With regard to ΔMPT, one-way ANOVA revealed statistically significant differences among the groups (p < 0.05). The data shown are means + or − SEM, n = 5–7 per group; *p < 0.05 compared to WT + PO.