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. 2017 Jan 20;7:41224. doi: 10.1038/srep41224

Figure 8. NKO Corneal Epithelial Cells upon LPS-induced-NFκB-Activation Showed Reduced Expression of Phosphorylated IκB (P IκB), IL6, IP10 and TNFα Compared to NWT Group.

Figure 8

(A) (i) Corneal epithelial cells isolated from NWT and NKO mice were treated with LPS in vitro; expression of PIκB was measured (ii) Graphic representation for PIκB data in (i) is shown. (B) (i) Corneal epithelial cells were treated with LPS or LPS + NFκB inhibitor, SC 154. Expression of PIκB and TNFα was tested. (ii and iii) Graphic representation of the relative expression of (ii) PIκB and (iii) TNFα, respectively in (i) is shown. (C) On treatment with LPS, expression of various inflammatory cytokines (IL6, IL10, INFγ, IP10, TNFα and IL12) was compared and analyzed by flow cytometry analysis. Results for (i) NWT group and (ii) NKO group are shown.