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. 2017 Jan 20;7:40768. doi: 10.1038/srep40768

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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SEM image in A1 shows a panoramic view of the ventricle, with lobe I (I) anterior to the choroid plexus (a, anterior, p, posterior). Magnification of the area shows the cilia that characterize the ependymal cells and a thickening that corresponds to the VMC (white arrow); this structure includes cells with only two cilia (yellow arrowheads in B,D) and with multiple small cilia (red arrowheads in B,D). These cells also contain several spheroid structures (white arrowheads in B), and blood vessels were observed near this area (white arrowhead in E). The VMC is different from the uniform cellular organization found laterally that consists of multiple ciliated cells shown in (C) I: lobule I; ChP: choroid plexus; a: anterior; p: posterior.