Table 1. Different Dynamical state.

S.No.	Dynamical state	Description	Reference
1.	First steady state	May correspond to normal cell.	72, 73, 74, 75
2.	First damped oscillation state	Stress (weak) induced cell that could able to repair back the changes in the cell and may come back to the normal condition.	72, 73, 74, 75
3.	Sustain oscillation state	Active state of the cell where active interaction of molecules are going on in the cell.	72, 73, 74, 75
4.	Second damped oscillation state	Damped oscillation state where the strong stress in p53 due to stress inducer nutlin and axin may become toxic to the system. In this state cell is associated with large stress, which cannot be repaired back and may probably go to apoptosis after some time.	see Supplementary information
5.	Second steady state	Apoptotic state where repairment of pathways cannot force cell to become normal in excess stress condition, thus cell chooses to destroy itself.	72, 73, 74, 75