Table 2. List of molecular species and their initial concentration.

S.No.	Species Name	Description	Notation	Initial Concentration (nM)
1.	Axin2	Initial Concentration Axin2 protein	x1	10.1
2.	Axin2 mRNA	Initial Concentration Axin2 mRNA	x2	0.02
3.	β-catenin	UnPhosphorylated β-catenin	x3	0.1
4.	β-cateninP	Phosphorylated β-catenin	x4	0.1
5.	β-cateninN	Nuclear β-catenin	x5	0.01
6.	Gsk3	Gsk3 protein	x6	5.0
7.	p53	unbound p53 protein	x7	10.0
8.	Mdm2	Unbound Mdm2 protein	x8	10.0
9.	Mdm2 mRNA	Mdm2 Messsenger mRNA	x9	0.0
10.	p53-Mdm2	Mdm2 and p53 complex	x10	95.0
11.	Nutlin	Unbound Nutlin	x11	5.0
12.	Nutlin-Mdm2	Nutlin Mdm2 complex	x12	0.0
13.	p53-Gsk3	p53 and Gsk3 complex	x13	0.0
14.	Dsh-activated	Activated Dsh protein	x14	0.5
15.	Dsh-Axin	The complex of Dsh and Axin2	x15	2.0
16.	Gsk3-Axin2	The complex of Gsk3 and Axin2	x16	2.0
17.	Lef1	The Lef1 protein in nucleus	x17	0.1
18.	β-catN-Lef1	The complex of β-catenin and Lef1 protein	x18	0.01
19.	Delta	The Delta protein	x19	1.68
20.	Delta mRNAC	The mRNA of Delta in the cytoplasm	x20	0.1
21.	Delta mRNAN	The mRNA of Delta in the nucleus	x21	0.1
22.	Axin2 mRNAC	The mRNA of Axin2 in the cytoplasm	x22	0.1
23.	Notch	The Notch protein	x23	0.5
24.	NICDC	Active Notch protein in the cytoplasm	x24	0.2
25.	NICDN	Active Notch protein in the nucleus	x25	0.0
26.	Lfring mRNA	The mRNA of Lunatic fringe protein	x26	0.01
27.	Lfring	The Lunatic fringe protein	x27	0.1
28.	Dsh-NICDC	The complex of Dsh and active Notch protein in cytoplasm	x28	0.1