Table 4.
Association between single nucleotide polymorphisms (SNPs) at lipoprotein lipase gene and lipid traits
| SNPs | Total cholesterol mmol/l | Triglycerides mmol/l | LDL-C mmol/l |
|---|---|---|---|
| SNP rs4922115 | |||
| GG | 4.9 ± 1.1 | 1.6 ± 1.0 | 3.1 ± 0.9 |
| GA | 4.8 ± 1.1 | 1.9 ± 1.8 | 3.0 ± 0.9 |
| AA | 4.7 ± 0.9 | 1.7 ± 0.8 | 2.9 ± 0.8 |
| Dominant model (GG vs GA + AA) (P value) | 0.4 | 0.001 | 0.1 |
| SNP rs1121923 | |||
| CC | 4.8 ± 1.1 | 1.7 ± 1.4 | 3.0 ± 0.9 |
| CT | 5.1 ± 1.0 | 1.7 ± 1.0 | 3.2 ± 0.9 |
| TT | 4.9 ± 0.6 | 1.4 ± 0.4 | 3.3 ± 0.4 |
| Dominant model (CC vs CT + TT) (P value) | 0.4 | 0.3 | 0.9 |
| SNP rs328 | |||
| CC | 4.9 ± 1.0 | 1.7 ± 1.1 | 3.1 ± 0.9 |
| CG | 4.9 ± 1.1 | 1.5 ± 0.9 | 3.1 ± 0.9 |
| GG | 5.0 ± 0.9 | 1.4 ± 0.5 | 3.2 ± 0.8 |
| Dominant model (CC vs CG + GG) (P value) | 0.3 | 0.1 | 0.3 |
| SNP rs285 | |||
| CC | 4.8 ± 1.1 | 1.7 ± 1.2 | 3.0 ± 0.8 |
| CT | 4.8 ± 1.1 | 1.5 ± 0.9 | 3.1 ± 0.9 |
| TT | 4.8 ± 1.0 | 1.4 ± 0.8 | 3.0 ± 0.8 |
| Dominant model (CC vs CT + TT) (P value) | 0.7 | 0.00009 | 0.4 |
LDL-c Low density lipoprotein cholesterol
Results are expressed as mean ± SD
P values adjusted for age, gender, body mass index and type 2 diabetes
Those p values that are in bold implicates those values that are significant after Bonferroni correction