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. 2017 Jan 19;16:14. doi: 10.1186/s12944-016-0389-y

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Cyclooxygenase-2 (COX-2)-like immunoreactivity in the frontal cortex. Brain sections of sham-operated and BCCAO/R rats are shown in (a, b) and (c, d), respectively. b, d represent a higher magnification of the microscopic fields squared in (a) and (c), respectively. Panels (a–d) are representative of observations carried out in 6 sham-operated and 6 BCCAO/R rats. Positive cell bodies are mostly distributed in the superficial cortical layers. m, molecular layer; wm, white matter. Scale bars: 50 μm