Table 2.
Meal Test Results for Faster Aspart and Insulin Aspart
| Faster aspart LSMean | IAsp LSMean | Treatment difference [95% CI] | P | |
|---|---|---|---|---|
| ΔPGav,0–2h (mmol/L) | 3.03 | 4.02 | −0.99 [–1.95; −0.03] | 0.044 |
| ΔPGav,0–2h (mg/dL) | 54.68 | 72.52 | −17.84 [–35.21; −0.46] | |
| ΔPGav,0–1h (mmol/L) | 1.89 | 2.39 | −0.50 [–1.07; 0.07] | 0.084 |
| ΔPGav,0–1h (mg/dL) | 34.13 | 43.14 | −9.01 [–19.28; 1.26] | |
| PG1h (mmol/L) | 10.05 | 11.68 | −1.64 [–2.79; −0.48] | 0.006 |
| PG1h (mg/dL) | 181.09 | 210.56 | −29.47 [–50.23; −8.71] | |
| PG2h (mmol/L) | 11.71 | 12.93 | −1.22 [–2.98; 0.53] | 0.168 |
| PG2h (mg/dL) | 211.01 | 233.07 | −22.06 [–53.64; 9.52] |
ΔPGav,0–2h was calculated as AUCPG,0-2h/2h − PGPre-dose where AUCPG,0-2h was the area under the PG concentration–time profile based on observed values and actual measurement times in relation to time of injection between 0 and 2 h.
AUC, area under the curve; faster aspart, faster-acting insulin aspart; IAsp, insulin aspart; LS, least squares; PG, plasma glucose.