Fig. 6.
Effects of pretreatment of quinpirole and DOI on haloperidol and clozapine-induced motor suppression without CAR test. a Motor activity (mean number of photobeam breaks) and b mean number of crossings of the five groups of rats on the last CAR training day (predrug), three drug test days (days 1 to 3), and two drug-free test days (drug-free CS-only and drug-free retraining). They were either treated subcutaneously with double vehicles, vehicle plus haloperidol (0.05 mg/kg), or clozapine (10.0 mg/kg), or quinpirole (1.0 mg/kg) plus haloperidol (0.05 mg/kg), or DOI (2.5 mg/kg) plus clozapine (10.0 mg/kg). *P<0.05 significantly different from the VEH+VEH group; #P<0.05 significantly different from the VEH+HAL or VEH+CLZ group