Table 2.
Predrug | Testa | |
---|---|---|
QUI-1.0 mg/kg (n=12) | 27.64±0.897 | 22.64±3.082 |
DOI-2.5 mg/kg (n=15) | 28.07±0.679 | 8.73±2.205* |
Rats from experiment 3 were first retrained in a 30-trial CAR session to reacquire avoidance responding. Only those that reached the retraining criterion (>70% avoidance responses) in that retraining session were used in this follow-up test. Rats tested with QUI-1.0 mg/kg consisted of rats that were treated with either vehicle, HAL or QUI+ HAL in experiment 3. Rats tested with DOI-2.5 mg/kg consisted of rats that were treated with vehicle, CLZ or DOI+CLZ in experiment 3
P<0.001 significantly different from the predrug condition
QUI (1.0 mg/kg, s) and DOI (2.5 mg/kg, s) were administered 40 min before a 30-trial CAR test