Table 3.
Baseline (BL) |
Low soy (LS) |
High soy (HS) |
Change (BL to LS) |
Change (BL to HS) |
Pdietb | Pethnicityc | Pinteractiond | |
---|---|---|---|---|---|---|---|---|
Serum E1 (ng/mL) | ||||||||
All | 106 | 116 | 107 | 12 | 4 | 0.42 | 0.33 | 0.53 |
Asian | 103 | 95 | 105 | −6 | 5 | |||
Non-Asian | 107 | 124 | 108 | 19 | 4 | |||
Serum E2 (pg/mL) | ||||||||
All women | 152 | 175 | 152 | 26 | 4 | 0.44 | 0.59 | 0.61 |
Asian | 148 | 151 | 149 | 4 | 4 | |||
Non-Asian | 154 | 184 | 153 | 33 | 5 | |||
NAF volume (µL) | ||||||||
All | 33 | 28 | 33 | −8 | −3 | 0.64 | 0.01 | 0.77 |
Asian | 22 | 26 | 29 | 1 | 4 | |||
Non-Asian | 37 | 29 | 34 | −11 | −6 | |||
NAF E1S (ng/mL) | ||||||||
All | 56 | 76 | 49 | 12 | −12 | 0.04 | 0.02 | 0.70 |
Asian | 48 | 67 | 45 | 11 | −6 | |||
Non-Asian | 60 | 78 | 50 | 12 | −14 | |||
NAF E2 (pg/mL) | ||||||||
All | 130 | 141 | 120 | −4 | −19 | 0.29 | 0.19 | 0.87 |
Asian | 103 | 128 | 111 | 6 | 6 | |||
Non-Asian | 140 | 145 | 123 | −7 | −27 |
Abbreviations: E1 estrone; E2 estradiol; E1S: estrone sulfate; NAF: nipple aspirate fluid.
P-values were obtained from mixed general linear models evaluating the difference between the low and high soy diet.
P-values for ethnicity as a fixed effect.
P-values represent interaction terms of ethnicity with dietary assignment, i.e., low soy diet vs. high soy diet.