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. 2016 Sep 13;123(2):345–356. doi: 10.1002/cncr.30321

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© 2016 The Authors. Cancer published by Wiley Periodicals, Inc. on behalf of American Cancer Society.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Disposition of the patients. ^aThree of the 5 deaths in this group were attributed to progression of the underlying cancer; 1 death was attributed to septic shock associated with acute ischemic enteritis and ileus, gram‐negative bacteremia, and respiratory failure; and 1 death was due to apparent tumor lysis syndrome. ^bIn all these patients, uridine triacetate was started more than 96 hours after 5‐fluorouracil or capecitabine was stopped. These deaths were attributed to sequelae of 5‐fluorouracil toxicities: acute respiratory distress syndrome (n = 1), multisystem organ failure secondary to sepsis (n = 1), and septic shock (n = 3).