FIG. 5.

Phylogenetic tree of 145 full-length bcr1 sequences (≥120 bp) from B. anthracis Ames, B. cereus ATCC 10987, and B. cereus ATCC 14579. The tree was based on the multiple alignment shown in Fig. 4 and was built by using the neighbor-joining method (32) applied to a matrix of pairwise distances between sequences. Distances were computed following Kimura's (19) two-parameter substitution model. Gaps (indels) were removed specifically for each pair of sequences compared. The scale bar shows the average number of nucleotide substitutions per site. bcr1 repeats are color coded based on the strain of origin: blue, B. cereus ATCC 14579; green, B. cereus ATCC 10987; red, B. anthracis Ames.