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. 2017 Jan 16;12:615–632. doi: 10.2147/IJN.S116583

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© 2017 Cantu et al. This work is published and licensed by Dove Medical Press Limited

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PTT ablation of MDA-MB-231 cells exposed to PEDOT-PMD NPs for 1.5 h and irradiated with 808-nm laser at 7 W/cm² after NPs were removed and replaced with Dulbecco’s phosphate-buffered saline.

Notes: Green represents live cells and red represents dead cells. Images are overlays of both green and red channels. Negative control consists of cells in NP-free media and not exposed to laser. Dark control consists of cells exposed to NPs, but not irradiated. Positive control consists of cells killed with methanol. Scale bars =200 μm.

Abbreviations: NPs, nanoparticles; PEDOT, poly(3,4-ethylenedioxythiophene); DBSA, 4-dodecylbenzenesulfonic acid; PSS-co-MA, poly(4-styrenesulfonic acid-co-maleic acid); PEDOT-PMD, PEDOT:PSS-co-MA:DBSA; PTT, photothermal therapy.