Table 1.
A list of some known drugs (of different categories) that can cause neuroleptic malignant syndrome
| Drug | Pharmacologic category |
|---|---|
| Amoxapine | Antidepressant, tetracyclic |
| Amisulpride | Nonconventional antipsychotic |
| Aripiprazole | Nonconventional antipsychotic |
| Chlorpromazine | Conventional antipsychotic, anticholinergic, and antihistaminic |
| Citalopram | SSRI antidepressant |
| Clozapine | Potent nonconventional antipsychotic |
| Desipramine | Antidepressant, tricyclic |
| Domperidone | Dopamine antagonist, antiemetic |
| Dosulepine | Antidepressant, tricyclic |
| Droperidol | Antipsychotic, antiemetic, and neuroleptanalgesic |
| Fluphenazine | Conventional antipsychotic |
| Haloperidol | Potent conventional antipsychotic |
| Lithium salts | Mood stabilizer |
| Metoclopramide | Antiemetic |
| Olanzapine | Nonconventional antipsychotic |
| Paliperidone | Nonconventional antipsychotic |
| Perphenazine | Potent conventional antipsychotic |
| Phenelzine | Antidepressant, anxiolytic, and irreversible nonselective MAOI |
| Prochlorperazine | Antiemetic, conventional antipsychotic |
| Promethazine | Antihistaminic, conventional antipsychotic |
| Quetiapine | Nonconventional antipsychotic |
| Reserpine | Antihypertensive, antipsychotic |
| Risperidone | Nonconventional antipsychotic |
| Tetrabenazine | VMA2 inhibitor, used in movement disorders (hyperkinesia) |
| Thioridazine | Nonconventional antipsychotic |
| Valproate | Anticonvulsant |
| Ziprasidone | Nonconventional antipsychotic |
Abbreviations: MAOI, mono amine oxidase inhibitor; SSRI, selective serotonin reuptake inhibitors; VMA2, vesicular monoamine transporter 2.